报告题目：Peptide-Mimicking Polymers as the Next Generation Bioactive Materials

报告人：刘润辉教授，华东理工大学

报告时间：2025年4月17日（周四）15:00

报告地点：化南S326会议室

报告人简介：刘润辉，教授、获国家杰出青年科学基金资助。2009年在美国普渡大学化学系获博士学位；2009年至2014年先后在美国加州理工学院和威斯康星大学-麦迪逊开展博士后研究；2014年底至今任华东理工大学教授。研究模拟多肽的氨基酸聚合物在生物材料和生物医药领域应用，致力于解决耐药微生物感染及植入材料生物相容性的挑战。近5年作为通讯作者在Sci. Transl. Med. (provisional accepted)、Nat. Microbiol.、Nat. Protoc.、Sci. Adv.、Nat. Commun. (7篇)、J. Am. Chem. Soc. (7篇)、Angew. Chem. Int. Ed. (5篇)、ACS Cent. Sci.、Adv. Mater.等期刊发表论文70余篇。成果入选华东理工大学首届年度十大学术进展。曾入选国家海外青年人才引进计划、东方学者、上海青年优秀学术带头人、霍尼韦尔学者、2019中国生物材料学会生物医用高分子材料分会优秀青年奖。

报告简介： Natural proteins/peptides possess important biological functions and are widely studied for biomedical and tissue engineering applications. However, their drawbacks such as intolerance to enzymatic degradation, expensiveness and difficulty for large-scale synthesis limit the practical application. We establish water-tolerant, fast and controllable polymerization method for convenient and scalable synthesis of amino acid polymers. By introducing unnatural amino acids, the resulting polymers resist proteolysis and have stable biological functions. Our recent studies demonstrate that our polymeric strategy is valid to mimic different types of natural peptides, with a wide range of applications as the next generation bioactive materials.