个人简介

武汉大学化学与分子科学学院教授，博士生导师，入选国家高层次人才青年项目和湖北省百人计划。在Nat. Catal. (1), Adv. Mater. (2), ACS Nano (3), Nano Lett. (2), Adv. Funct. Mater. (6), Nano Today (1), Chem. Mater. (1), Small (4), Biomaterials (3)等国际著名期刊发表SCI论文65篇(其中第一作者或通讯作者论文36篇，ESI高被引论文6篇，影响因子>10的论文25篇)，被引3900余次，H因子36，基于Web of Science数据。授权/受理专利5项(中国专利3项，美国专利2项)。研究成果被Physics World, Nanowerk, Phys.org, EurekAlert, Materialsviewschina, Nanochemistry等多个学术网站报道，并有多篇研究论文被选为封面文章和 VIP 文章。研究成果受到国内外同行的广泛关注和认可，研究论文多次被Chem. Rev.、Chem. Soc. Rev.等顶级期刊正面引用和评述。主持多项国家自然科学基金项目以及省部级课题，长期招收博士后、博士生与硕士生，欢迎感兴趣的同学加入。

教育经历

2007.09-2011.06    武汉大学化学与分子科学学院    大学本科

2011.09-2016.06    武汉大学化学与分子科学学院    博士研究生

工作经历

2016.08-2019.11    以色列耶路撒冷希伯来大学化学系  博士后

2019.11-2020.11    武汉大学化学与分子科学学院  特聘研究员

2020.12-至今        武汉大学化学与分子科学学院  教授

研究方向

生物医用材料、药物递送、肿瘤靶向治疗

代表成果

1. Wang Jia-Wei, Chen Qi-Wen, Luo Guo-Feng, Ji Ping, Han Zi-Yi, Song Wen-Fang, Chen Wei-Hai,* Zhang Xian-Zheng.* Interference of Glucose Bioavailability of Tumor by Engineered Biohybrids for Potentiating Targeting and Uptake of Antitumor Nanodrugs. Nano Letters 2022, 22, 8735-8743.

2. Liang Jun-Long, Niu Mei-Ting, Luo Guo-Feng, Zhang Shi-Man, Huang Qian-Xiao, Jin Xiao-Kang, Lu Zhibing, Chen Wei-Hai,* Zhang Xian-Zheng.* Tailor-Made Biotuner against Colorectal Tumor Microenvironment to Transfer Harms into Treasures for Synergistic Oncotherapy. Nano Today 2022, 47, 101662.

3. Wang Jia-Wei, Chen Qi-Wen, Luo Guo-Feng, Han Zi-Yi, Song Wen-Fang, Yang Juan, Chen Wei-Hai,* Zhang Xian-Zheng.* A Self-Driven Bioreactor Based on Bacterium-Metal-Organic Framework Biohybrids for Boosting Chemotherapy via Cyclic Lactate Catabolism. ACS Nano 2021 15, 17870-17884.

4. Liang Jun-Long, Luo Guo-Feng, Chen Wei-Hai,* Zhang Xian-Zheng.* Recent advances in engineered materials for immunotherapy-involved combination cancer therapy. Advanced Materials 2021, 33, 2007630.

5. Chen Wei-Hai, Vázquez-González Margarita, Zoabi Amani, Abu-Reziq Raed, Willner Itamar.* Biocatalytic Cascades Driven by Enzymes Encapsulated in Metal-Organic Framework Nanoparticles. Nature Catalysis 2018, 1, 689-695.

6. Chen Wei-Hai, Luo Guo-Feng, Zhang Xian-Zheng.* Recent Advances in Subcellular Targeted Cancer Therapy Based on Functional Materials. Advanced Materials 2019, 31, 1802725.

7. Chen Wei-Hai, Zhou Zhixin, Luo Guo-Feng, Neumann Ehud, Marjault Henri-Baptiste, Stone David, Nechushtai Rachel, Willner Itamar.* Photosensitized H2-Evolution and NADPH-Formation by Photosensitizer/Carbon Nitride Hybrid Nanoparticles. Nano Letters 2019, 19, 9121-9130.

8. Chen Wei-Hai, Luo Guo-Feng, Sohn Yang Sung, Nechushtai Rachel, Willner Itamar.* Enzyme-Driven Release of Loads from Nucleic Acid-Capped Metal-Organic Framework Nanoparticles. Advanced Functional Materials 2019, 29, 1805341.

9. Chen Wei-Hai, Luo Guo-Feng, Vázquez-González Margarita, Cazelles Rémi, Sohn Yang Sung, Nechushtai Rachel, Mandel Yossi, Willner Itamar.* Glucose-Responsive Metal-Organic-Framework Nanoparticles Act as "Smart" Sense-and-Treat Carriers. ACS Nano 2018, 12, 7538-7545.

10. Chen Wei-Hai, Liao Wei-Ching, Sohn Yang Sung, Michael Fadeev, Cecconello Alessandro, Nechushtai Rachel, Willner Itamar.* Stimuli-Responsive Nucleic Acid-Based Polyacrylamide Hydrogel-Coated Metal-Organic Framework Nanoparticles for Controlled Drug Release. Advanced Functional Materials 2018, 28, 1705137.