个人简介

武汉大学化学与分子科学学院副教授，博士导师，武汉大学珞珈青年学者；先后主持4项国家自然科学基金面上项目；作为研究骨干参与国家重点研究计划、中国科学院战略性先导科技专项（A类）等多个科研项目。

教育经历

1999.09-2003.06    河北师范大学化学与材料科学学院   大学本科

2003.09-2008.06    武汉大学化学与分子科学学院    博士研究生

工作经历

2008.07-2014.11     武汉大学   讲师

2009.10-2012.03    日本京都大学物质细胞统合研究所（iCeMS）   博士后

2014.12-至今         武汉大学    副教授

研究方向

微流控芯片液体活检、生物传感分析

代表成果

1. Cheng, S. B.; Chen, M. M.; Wang, Y. K.; Sun, Z. H.; Qin, Y.; Tian, S.; Dong, W. G.*; Xie, M.*; Huang, W. H., A Three-Dimensional Conductive Scaffold Microchip for Effective Capture and Recovery of Circulating Tumor Cells with High Purity. Anal. Chem. 2021, 93 (18), 7102-7109.

2.Cheng, S.-B.; Wang, M.; Zhang, C.; Chen, M.-M.; Wang, Y.-K.; Tian, S.; Zhan, N.; Dong, W.-G.; Xie, M.*; Huang, W.-H.*, Flexible Three-Dimensional Net for Intravascular Fishing of Circulating Tumor Cells. Anal. Chem. 2020, 92 (7), 5447-5455.

3. Tian, S.; Cheng, S.-B.; Guo, Y.-Y.; Xie, M.*; Zhan, N.; Zeng, Z.; Huang, W.-H.; Dong, W.-G. *, High Efficient Isolation of Tumor Cells by a Three Dimensional Scaffold Chip for Diagnosis of Malignant Effusions. ACS Appl. Bio Mater. 2020, 3 (4), 2177-2184.

4. Cheng, S. B.; Chen, M. M.; Wang, Y. K.; Sun, Z. H.; Xie, M.*; Huang, W. H.*, Current techniques and future advance of microfluidic devices for circulating tumor cells. Trac-Trends Anal. Chem. 2019, 117, 116-127.

5.Chen, Z.; Cheng, S. B.; Cao, P.; Qiu, Q. F.; Chen, Y.; Xie, M.*; Xu, Y.*; Huang, W. H., Detection of exosomes by ZnO nanowires coated three-dimensional scaffold chip device. Biosens. Bioelectron. 2018, 122, 211-216.

6. Cheng, S. B.; Xie, M.; Chen, Y.; Xiong, J.; Liu, Y.; Chen, Z.; Guo, S.; Shu, Y.; Wang, M.; Yuan, B. F.; Dong, W. G.; Huang, W. H., Three-Dimensional Scaffold Chip with Thermosensitive Coating for Capture and Reversible Release of Individual and Cluster of Circulating Tumor Cells. Anal. Chem. 2017, 89 (15), 7924-7932. (cofirst author)

7. Cheng, S. B.; Xie, M.; Xu, J. Q.; Wang, J.; Lv, S. W.; Guo, S.; Shu, Y.; Wang, M.; Dong, W. G.; Huang, W. H., High-Efficiency Capture of Individual and Cluster of Circulating Tumor Cells by a Microchip Embedded with Three-Dimensional Poly(dimethylsiloxane) Scaffold. Anal. Chem. 2016, 88 (13), 6773-6780. (cofirst author)

8. Lu, N. N.; Xie, M.; Wang, J.; Lv, S. W.; Yi, J. S.; Dong, W. G.; Huang, W. H., Biotin-triggered decomposable immunomagnetic beads for capture and release of circulating tumor cells. ACS Appl Mater Interfaces 2015, 7 (16), 8817-26. (cofirst author)

9. Xie, M.; Lu, N.-N.; Cheng, S.-B.; Wang, X.-Y.; Wang, M.; Guo, S.; Wen, C.-Y.; Hu, J.; Pang, D.-W.; Huang, W.-H., Engineered Decomposable Multifunctional Nanobioprobes for Capture and Release of Rare Cancer Cells. Anal. Chem. 2014, 86 (9), 4618-4626.

10. Guo, S.; Chen, Y. Q.; Lu, N. N.; Wang, X. Y.; Xie, M.*; Sui, W. P.*, Ultrasonication-assisted one-step self-assembly preparation of biocompatible fluorescent-magnetic nanobeads for rare cancer cell detection. Nanotechnology 2014, 25 (50), 505603.