个人简介

武汉大学化学与分子科学学院教授，博士生导师

教育经历

1986年于武汉大学获学士学位，1989年于武汉大学获硕士学位，1995年于武汉大学获博士学位（导师：陈远荫教授）。

工作经历

1989年至1998年在武汉大学化学系先后任助教、讲师、副教授。1998年10月至2000年9月在日本九州大学（Kyushu University）作博士后研究。2001年3月至2004年8月在美国得克萨斯大学（The University of Texas at Austin）作Research Associate。自2004年8月起在武汉大学化学学院高分子系任教授。

研究方向

代表成果

1.Peng Q, Chen FJ, Zhong ZL*, Zhuo RX, “Enhanced gene transfection capability of polyethylenimine by incorporating boronic acid groups”, Chem. Comm. 2010, 46, 5888-5890.

2.Hu C, Peng Q, Chen FJ, Zhong ZL*, Zhuo RX*, “Low Molecular Weight Polyethylenimine Conjugated Gold Nanoparticles as Efficient Gene Vectors”，Bioconjugate Chem. 2010, 21, 836-843.

3.ZhangXJ，ChengJ，Wang QR，Zhong ZL*，Zhuo RX*，“Miktoarm Copolymers Bearing One Poly(ethylene glycol) Chain and Several Poly(epsilon-caprolactone) Chains on a Hyperbranched Polyglycerol Core”，Macromolecules, 2010,43, 6671-6677.

4.Hargrove AE, Zhong ZL, Sessler JL, Anslyn EV*, “Algorithms for the determination of binding constants and enantiomeric excess in complex host : guest equilibria using optical measurements”, New J. Chem.2010, 34, 348-354.

5.Zhang XJ, Mei HJ, Hu C, Zhong ZL*, Zhuo RX*, “Amphiphilic Triblock Copolycarbonates with Poly(glycerol carbonate) as Hydrophilic Blocks”, Macromolecules, 2009,42, 1010-1016.

6.Peng Q, Hu C, Cheng J, Zhong ZL*, Zhuo RX, “Influence of Disulfide Density and Molecular Weight on Disulfide Cross-Linked Polyethylenimine as Gene Vectors”, Bioconjugate Chem. 2009, 20, 340-246.

7.Peng Q, Zhong ZL* and Zhuo RX，“Disulfide Cross-Linked Polyethylenimines (PEI) Prepared via Thiolation of Low Molecular Weight PEI as Highly Efficient Gene Vectors”Bioconjugate Chem.2008, 19, 499-506.

8.Mei HJ, Zhong ZL* Long FH, Zhuo RX*, “Synthesis and Characterization of Novel Glycerol-Derived Polycarbonates with Pendant Hydroxyl Groups”, Macromol. Rapid Commun. 2006, 27, 1894–1899.

9.Zhong ZL, PostnikovaBJ, HanesRE, LynchVM, AnslynEV, “Large pKa Shifts of a-Carbon Acids Induced by Copper(II) Complexes”，Chem. Eur. J.2005，11，2385-2394.

10.Zhu L, ZhongZL, AnslynEV, “Guidelines in Implementing Enantioselective Indicator-Displacement Assays for -Hydroxycarboxylatesand Diols”,J. Am. Chem. Soc. 2005, 127, 4260-4269.

11.Wright AT, Zhong ZL, Anslyn EV, “A functional assay for heparin in serum using a designed synthetic receptor”, Angew. Chem. Int. Ed.2005, 44, 5679-5682.

12.Zhong ZL, Snowden TS, Best MD, Anslyn EV, “Rate of Enolate Formation Is Not Very Sensitive to the Hydrogen Bonding Ability of Donors to Carboxyl Oxygen Lone Pair Acceptors; A Ramification of the Principle of Non-Perfect Synchronization for General-Base-Catalyzed Enolate Formation”, J. Am. Chem. Soc. 2004, 126, 3488-3495.

13.Wright AT, Griffin MJ, Zhong ZL, McCleskey SC, Anslyn EV, McDevitt JT, “Differential receptors create patterns that distinguish various proteins”, Angew. Chem. Int. Ed.2005, 44, 6375-6378.

14.Zhong ZL, Anslyn EV, “Controllingthe Oxygenation Level of Hemoglobin by Using a Synthetic Receptor for 2,3-Bisphosphoglycerate”, Angew. Chem. Int. Ed. 2003, 42, 3005-3008.

15.Zhong ZL, Anslyn EV, “A Colorimetric Sensing Ensemble for Heparin”, J. Am. Chem. Soc. 2002, 124, 9014-9015.