师资队伍

  • 两院院士
  • 高层次人才
  • 在职教师
  • 荣休教师

董秀琴

办公地点:化北-409

联系电话:

电子邮箱:xiuqindong@whu.edu.cn; xiuqindong-chem@whu.edu.cn

团队主页:http://wanglab.whu.edu.cn/

个人简介

武汉大学化学与分子科学学院副教授,硕士生导师,博士生导师,围绕开发新型手性膦配体和高效不对称催化体系展开研究工作,主持3项国家级基金(2项面上项目,1项青年基金)和3项省部级基金(含湖北省杰出青年项目),以第一作者或通讯作者(含共同)在Acc. Chem. Res.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、CCS Chem.、Fundamental Res.、Chem. Sci.、ACS Catal.、Org. Lett.、Chem. Commun.、Org. Chem. Front.等杂志上发表论文七十余篇,其中20篇被评述杂志Synfacts进行正面评价,2篇被选为VIP文章,4篇被选为Hot paper,3篇被作为封面,1篇被J. Am. Chem. Soc.的Spotlights予以积极评价,1篇被《有机化学》亮点评述。入选2017年度湖北省“楚天学者计划”(楚天学子),2019年——2025年任第三届和第四届《Chinese Chemical Letters》青年编委会委员,获得2020年武汉大学本科优秀教学业绩奖和学院青年教师教学竞赛一等奖。


教育经历

2003.09-2007.07    黄冈师范学院化学学院     大学本科

2007.09-2012.07    武汉大学化学与分子科学学院  博士研究生    


工作经历

2012.09-2014.09   香港科技大学化学系   博士后

2015.01-至今        武汉大学化学与分子科学学院   副教授


研究方向

1. 发展新型手性膦配体及其在不对称催化反应中的应用研究、2. 开发不对称协同催化体系及其在催化反应中的应用研究3. 运用不对称催化反应高效构建手性药物或生物活性分子关键中间体


代表成果

1. Zhi-Yuan Yi, Lu Xiao, Xin Chang, Xiu-Qin Dong,* and Chun-Jiang Wang,* Iridium-Catalyzed Asymmetric Cascade Allylation/Retro-Claisen Reaction, J. Am. Chem. Soc., 2022, 144, 20025.

2. Xi-Shang Sun, Xin-Yu Diao, Xiu-Qin Dong,* and Chun-Jiang Wang,* Base- promoted cascade β-F-elimination/electrocyclization/Diels-Alder/retro-Diels-Alder reaction: efficient access to δ-carboline derivatives, Chem. Sci., 2022, 13, 10448.

3. Gongyi Liu, Lini Zheng, Kui Tian, Haifeng Wang, Lung Wa Chung, Xumu Zhang* and Xiu-Qin Dong,* Ir-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles: Scope Investigations and Mechanistic Studies, CCS Chem., 2022, DOI: 10.31635/ccschem.022.202101643.

4. Lu Xiao, Bo Li, Fan Xiao, Cong Fu, Liang Wei, Yanfeng Dang*, Xiu-Qin Dong,* and Chun-Jiang Wang,* Stereodivergent synthesis of enantioenriched azepino[3,4,5-cd]-indoles via cooperative Cu/Ir-catalyzed asymmetric allylic alkylation and intramolecular Friedel–Crafts reaction, Chem. Sci., 2022, 13, 4801.

5. Zhengyu Han, Gang Liu, Xuanliang Yang, Xiu-Qin Dong,* and Xumu Zhang,* Enantiodivergent Synthesis of Chiral Tetrahydroquinoline Derivatives via Ir-Catalyzed Asymmetric Hydrogenation: Solvent-Dependent Enantioselective Control and Mechanistic Investigations, ACS Catal., 2021, 11, 7281.

6. Qingyang Zhao,* Caiyou Chen, Jialin Wen, Xiu-Qin Dong,* Xumu Zhang,* Noncovalent Interaction-assisted Ferrocenyl Phosphine Ligands in Asymmetric Catalysis, Acc. Chem. Res., 2020, 53, 1905.

7. Yuanhua Liu, Zhiyuan Yi, Xuanliang Yang, Heng Wang, Congcong Yin, Minyan Wang,* Xiu-Qin Dong,* and Xumu Zhang,* Efficient Access to Chiral 2- Oxazolidinones via Ni-Catalyzed Asymmetric Hydrogenation: Scope Study, Mechanistic Explanation, and Origin of Enantioselectivity, ACS Catal., 2020, 10, 11153

8. Zhengyu Han, Gang Liu, Rui Wang, Xiu-Qin Dong,* Xumu Zhang,* Highly Efficient Ir-Catalyzed Asymmetric Hydrogenation of Benzoxazinones and Derivatives with Brønsted Acid Cocatalyst, Chem. Sci., 2019, 10, 4328.

9. Gongyi Liu, Heng Zhang, Yi Huang, Zhengyu Han, Gang Liu, Yuanhua Liu; Xiu-Qin Dong,* Xumu Zhang,* Efficient synthesis of chiral 2,3-dihydrobenzo[b]thiophene 1,1-dioxides via Rh-catalyzed hydrogenation, Chem. Sci., 2019, 10, 2507.

10. Caiyou Chen, Zhefan Zhang, Shicheng Jin, Xiangru Fan, Mingyu Geng, Yan Zhou, Songwei Wen, Xinrui Wang, Lung Wa Chung,* Xiu-Qin Dong,* Xumu Zhang,* Enzyme-Inspired Chiral Secondary-Phosphine-Oxide Ligand with Dual Noncovalent Interactions for Asymmetric Hydrogenation, Angew. Chem. Int. Ed., 2017, 56, 6808.