师资队伍

  • 两院院士
  • 高层次人才
  • 在职教师
  • 荣休教师

吕辉

办公地点:

联系电话:027-68755925

电子邮箱:huilv@whu.edu.cn

团队主页:https://www.researchgate.net/profile/Hui_Lv3/contributions

个人简介

武汉大学化学与分子科学学院副教授,博士生导师


教育经历

1999.09-2003.06      湘潭大学    大学本科

2003.09-2010.06      中国科学院化学研究所    博士研究生


工作经历

2010.08-2012.08      新加坡南洋理工大学        博士后

2012.10-2013.10      中国科学院化学研究所    任助理研究员

2013.11-至今           武汉大学化学与分子科学学院    副教授


研究方向

1、过渡金属催化的不对称催化反应研究

2、新型手性膦配体的合成及应用

3、催化反应在药物中间体及生物活性分子合成中的应用


代表成果

1.Cai You, Shuailong Li, Xiuxiu Li,Hui Lv*, Xumu Zhang*, Enantioselective Rh-Catalyzed Anti-Markovnikov Hydroformyla-tion of 1,1-Disubstituted Allylic Alcohols and Amines: An Efficient Route to Chiral Lactones and Lactams,ACS Catal.2019, 9, 8529.

2.ShuailongLi, Zhuangxing Li, Cai You,Hui Lv*, Xumu Zhang, Recent Advances in Asymmetric Hydroformylation,Chinese Journal of Organic Chemistry,2019, 39, 1568-1582. (In Chinese)

3.Xiuxiu Li,Cai You,Jiaxin Yang, Shuailong Li, Dequan Zhang,Hui Lv*, Xumu Zhang*,Asymmetric Hydrocyanation of Alkenes without HCN,Angew. Chem. Int. Ed.2019,58, 10928.

4.Xu Deng, Li-Yang Shi, Jialing Lan, Yuqing Guan, Xiaoyong Zhang,Hui Lv*, Lung Wa Chung*, Xumu Zhang*, Enantioselective Rhodium-Catalyzed Cycloisomerization of 1,6-Allenynes to access 5/6-Fused Bicyclo[4.3.0]nonadienes,

Nat. Commun.,2019,10, 949.

5.Yu-Qing Guan, Zhengyu Han, Xiuxiu Li, Cai You, Xuefeng Tan,Hui Lv*, Xumu Zhang, A Cheap Metal for a Challenging Task: Nickel-Catalyzed Highly Diastereo- and Enantioselective Hydrogenation of Tetrasubstituted Fluorinated Enamides,Chem. Sci.2019, 256-259.

6.Jiao Long, Liyang Shi, Xiong Lia,Hui Lv*, Xumu Zhang*, Rhodium-Catalyzed Highly Regio- and Enantioselective Hydrogenation of Tetrasubstituted Allenyl Sulfones: An Efficient Access to Chiral Allylic Sulfones,Angew. Chem. Int. Ed.2018,57,13248-13251

7.Jiao Long, Wenchao Gao, Yuqing Guan,Hui Lv*, Xumu Zhang, Nickel-catalyzed Highly Enantioselective Hydrogenation of β-Acetylamino Vinylsulfones: An Efficient Access to Chiral β‑Amido Sulfones,Org. Lett.,201820, 5914–5917.

8.Cai You, Shuailong Li, Xiuxiu Li, Jialing Lan, Yuhong Yang, Lung Wa Chung, Hui Lv,* Xumu Zhang*, Design and Application of Hybrid Phosphorus Ligands for Enanti-oselective Rh-Catalyzed Anti-Markovnikov Hydroformylation of Unfunctionalized 1,1-Disubstituted Alkenes,J. Am. Chem. Soc.,2018,140, 4977–4981.

9.Cai You, Xiuxiu Li, Yuhong Yang, Yu-Sheng Yang, Xuefeng Tan, Shuailong Li, Biao Wei,Hui Lv*, Lung-Wa Chung*, Xumu Zhang*,Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation,Nat. Commun.,2018,9, 2045

10.Xiuxiu Li, Cai You, Yusheng Yang,Yuhong Yang, Pan Li, Guoxian Gu, Lung Wa Chung,Hui Lv*, Xumu Zhang*, Rhodium-catalyzed asymmetric hydrogenation of β-cyanoacrylate esters with the assistance of a single hydrogen bond in a precise position,Chem. Sci.,2018,9, 1919-1924

11.Zhichao Xiong, Chengfeng Pei, Peng Xue,Hui Lv*, Xumu Zhang*, Highly Enantioselective Transfer Hydrogenation of Racemica-Substitutedb-keto SulfonamidesviaDynamic Kinetic Resolution,Chem. Commun.2018,54, 3883-3886.